According to the World Health Organization, in any population, for every person suffering from IDA, there are three with iron deficiency (IAD). The risk group for the development of anemia includes children, women of reproductive age and the elderly. A special group among them are girls of pubertal age, who have a high potential for the formation of various organ dysfunctions. The purpose of this work was to study the clinical and anamnestic features of the dynamics and transformation of iron deficiency anemia in adolescent girls. Object and methods of the study: adolescent girls aged 12-14 years (n=177) of the Uzbek population, respectively, with LAD (45), mild IDA (56) and moderate (25), and the control group (51). For the study, whole blood and serum of adolescent girls with IDA were used. General clinical, instrumental, biochemical and statistical methods were used. Results: From the data of our material it follows that the clinical picture of IDA in schoolgirls was somewhat transformed and among them the syndrome of decreased immunological resistance of the body and gastrointestinal syndrome began to prevail, their frequency increased by more than 2-5 times compared to the above authors. The clinical picture of iron deficiency anemia in adolescent girls is characterized by polymorphism of symptoms and syndromes, which indicates the involvement of many organs and systems in the pathological process. It is concluded that it is necessary to update data on the clinical symptoms of ID in adolescent girls, depending on age, gender and regions of residence.

Under the significant global influence of environmental obesity and due to access to food, non-traditional, overweight and obesity among children and adolescents has become a serious problem in the developed world, followed by developing countries. The incidence of pathology is progressively increasing, doubling every three decades and affecting the negative health of the population to the same extent as traditional global problems, since they are hunger and infectious diseases, obesity is called the modern non-communicable epidemic. Pathology is the fifth leading risk of death worldwide and contributes significantly to the occurrence and development of complications that lead to world-wide mortality, including diabetes, heart disease and some forms of cancer. Overweight and obesity were estimated to be causative factors for 3.4 million deaths worldwide in 2010, and it has been suggested that the growing trend towards obesity could significantly reduce life expectancy. Data from several studies show that the incidence of obesity in developing countries is increasing. At present, income countries, small and middle children face a double burden of nutrition problems, on the one hand they continue to struggle with malnutrition, and on the other hand, it has to face the rapid growth of non-communicable pathologies such as obesity and overweight.

53 children and adolescents with various degrees of obesity underwent clinical, laboratory and psychological examination. It has been established that obese children and adolescents have impaired ideas about food. A comprehensive assessment of the psychological state of children and adolescents with obesity showed that it depends on the level of body mass index. In obese children and adolescents who have been examined, there is a violation of psychological adaptation, especially in severe cases. This fact requires the inclusion of psychotherapeutic methods in the complex treatment of children with obesity as a mandatory component of treatment in the treatment of children and adolescents with obesity. It also highlights the need for treatment programs for patients with eating disorders.

The immune status has been studied at 35 HIV-infected of children with ARS. The control group of comparison consisted from 14 practically healthy faces. At a HIV-infected of patients with ARS has revealed deep infringements of the immune status, especially from the T-link of immunity and its subpopulations, and also frustration humoral an immunity link, suppression of proinflammatory cytokine IL-10 and increase proinflammatory IFN-?. Under the influence of the spent treatment have not revealed certain changes from the immune status at patients. It is possible to ascertain only positive changes of maintenance IL-10 and parallel decrease IFN-? in dynamics of treatment. In the main group there were 25 HIV-infected patients with ARS, and in the control group there were 14 practically healthy children of the same age who did not have a history of ARS and HIV. All 35 HIV-infected children were registered with the Bukhara Regional AIDS Center. Patients received antiretroviral therapy, antibacterial, anti-inflammatory and local therapy in a hospital setting.